Article
Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection.
Parasitology - 1 Feb 2015
Chang Hsiao-Han, Hartl Daniel L
Abstract excerpt
Detecting signals of selection in the genome of malaria parasites is a key to identify targets for drug and vaccine development. Malaria parasites have a unique life cycle alternating between vector and host organism with a population bottleneck at each transition. These recurrent bottlenecks cou...
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