Article

Mode and tempo of microsatellite length change in a malaria parasite mutation accumulation experiment

2019-02-25

Abstract excerpt

Microsatellite sequences are widely assumed to evolve neutrally, but also play an important role in bacterial pathogenesis, human disease and transcript abundance. The malaria parasite Plasmodium falciparum genome is extraordinarily AT-rich, containing 132,449 microsatellites-stretches of perfect 1-9 bp repeats between 10-1000bp, which comprise 10.74% of the 23 Mb genome. This project was designed to determine th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2e60644e-c3c4-5b74-9454-c13aa239b019
DOI: 10.1101/560516

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mode and tempo of microsatellite length change in a malaria parasite mutation accumulation experimentDOI 10.1101/560516Read

Complex mutations in a high proportion of microsatellite loci from the protozoan parasite Plasmodium falciparum.Semantic proximity Read

Microsatellite analysis of malaria parasites.Semantic proximity Read

<i>De Novo</i> Mutations Resolve Disease Transmission Pathways in Clonal MalariaSemantic proximity Read

De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria.Semantic proximity Read

Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen FamiliesSemantic proximity Read

Two distinct modes of microsatellite mutation processes: evidence from the complete genomic sequences of nine species.Semantic proximity Read

Genome-wide microsatellite characteristics of five human Plasmodium species, focusing on Plasmodium malariae and P. ovale curtisi.Semantic proximity Read

Extreme mutation bias and high AT content in Plasmodium falciparum.Semantic proximity Read

Detecting sequence variants in clinically important protozoan parasites.Semantic proximity Read

Single-cell sequencing of the small and AT-skewed genome of malaria parasites.Semantic proximity Read

Detecting number of clones, and their relative abundance, of a malaria parasite (Plasmodium mexicanum) infecting its vertebrate host.Semantic proximity Read

[Microsatellite markers and their application in genetic diversity research of Plasmodium spp].Semantic proximity Read