Article
Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer.
BMC cancer - 16 May 2009
Zieger Karsten, Wiuf Carsten, Jensen Klaus Møller-Ernst, Ørntoft Torben Falck, Dyrskjøt Lars
Abstract excerpt
BACKGROUND: Non-muscle invasive bladder neoplasms with invasion of the lamina propria (stage T1) or high grade of dysplasia are at "high risk" of progression to life-threatening cancer. However, the individual course is difficult to predict. Chromosomal instability (CI) is associated with high tumor stage and grade, and possibly with the risk of progression. METHODS: To investigate the relationship between CI and...
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