Article
Association of the TNF-α G-308A polymorphism with TNF-inhibitor response in sarcoidosis.
The European respiratory journal - 1 Jun 2014
Wijnen Petal A, Cremers Johanna P, Nelemans Patty J, Erckens Roel J, Hoitsma Elske, Jansen Tim L, Bekers Otto, Drent Marjolein
Abstract excerpt
Responsiveness to tumour necrosis factor (TNF) inhibitors has been associated with the TNF-α G-308A polymorphism in rheumatoid arthritis. The aim of this study was to examine the association between the presence of this polymorphism and the response to TNF inhibitors in patients with refractory sarcoidosis. Patients (n=111) who started TNF-inhibitor treatment (76 infliximab, 35 adalimumab) were followed for at...
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