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Article

Association of the TNFRSF1A genotype with lung function impairment in patients with sarcoidosis.

Scientific reports - 5 May 2026

Lunde A G, Romundstad S, Henriksen A H, Sorger H, Boerner E, Schröder N, Bonella F

Abstract excerpt

The single-nucleotide polymorphism (SNP) rs1800693 in the tumor necrosis factor receptor 1 (TNFR1) gene leads to the formation of a protein-mimicking effect of TNF-α inhibitors, which are agents used to treat sarcoidosis. We investigated the association between rs1800693 and disease progression in two populations with non-Lofgren sarcoidosis (nLS). We genotyped two nLS cohorts (Ruhrlandklinik, Germany, n = 108,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42086639
DOI: 10.1038/s41598-026-51077-x
PMCID: PMC13333820

Genes

TNF
TNFRSF1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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