Article
The role of tumor necrosis factor alpha G-308A polymorphisms in the course of pulmonary sarcoidosis.
Tissue antigens - 1 Mar 2010
Wijnen P A, Nelemans P J, Verschakelen J A, Bekers O, Voorter C E, Drent M
Abstract excerpt
This study was designed to evaluate the relationship between the presence of tumor necrosis factor (TNF) polymorphisms, human leukocyte antigen (HLA)-DRB1*03 linkage and the prognosis of sarcoidosis. In a retrospective case-control study, TNF-alpha G-308A, TNF-alpha G-238A, lymphotoxin-alpha (LTA) and HLA-DRB1*03 were genotyped in 625 sarcoidosis patients. These patients were classified into 298 patients with...
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