Article
Fascin is required for blood cell migration during Drosophila embryogenesis.
Development (Cambridge, England) - 1 Aug 2009
Zanet Jennifer, Stramer Brian, Millard Thomas, Martin Paul, Payre François, Plaza Serge
Abstract excerpt
Fascin is well characterized in vitro as an actin-bundling protein and its increased expression is correlated with the invasiveness of various cancers. However, the actual roles and regulation of Fascin in vivo remain elusive. Here we show that Fascin is required for the invasive-like migration of blood cells in Drosophila embryos. Fascin expression is highly regulated during embryonic development and, within the...
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