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Article

Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF.

PloS one - 1 Jan 2012

Jönsson Friederike, Gurniak Christine B, Fleischer Bernhard, Kirfel Gregor, Witke Walter

Abstract excerpt

Dynamic changes in the actin cytoskeleton are essential for immune cell function and a number of immune deficiencies have been linked to mutations, which disturb the actin cytoskeleton. In macrophages and dendritic cells, actin remodelling is critical for motility, phagocytosis and antigen presentation, however the actin binding proteins, which control antigen presentation have been poorly characterized. Here we...

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Identifiers

PMID: 22558315
DOI: 10.1371/journal.pone.0036034
PMCID: PMC3338623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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