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Article

Systems biology-based identification of Mycobacterium tuberculosis persistence genes in mouse lungs.

mBio - 18 Feb 2014

Dutta Noton K, Bandyopadhyay Nirmalya, Veeramani Balaji, Lamichhane Gyanu, Karakousis Petros C, Bader Joel S

Abstract excerpt

UNLABELLED: Identifying Mycobacterium tuberculosis persistence genes is important for developing novel drugs to shorten the duration of tuberculosis (TB) treatment. We developed computational algorithms that predict M. tuberculosis genes required for long-term survival in mouse lungs. As the input, we used high-throughput M. tuberculosis mutant library screen data, mycobacterial global transcriptional profiles in...

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Identifiers

PMID: 24549847
DOI: 10.1128/mBio.01066-13
PMCID: PMC3944818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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