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Article

Systems level mapping of metabolic complexity in Mycobacterium tuberculosis to identify high-value drug targets.

Journal of translational medicine - 11 Oct 2014

Vashisht Rohit, Bhat Ashwini G, Kushwaha Shreeram, Bhardwaj Anshu, Brahmachari Samir K

Abstract excerpt

BACKGROUND: The effectiveness of current therapeutic regimens for Mycobacterium tuberculosis (Mtb) is diminished by the need for prolonged therapy and the rise of drug resistant/tolerant strains. This global health threat, despite decades of basic research and a wealth of legacy knowledge, is due to a lack of systems level understanding that can innovate the process of fast acting and high efficacy drug...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25304862
DOI: 10.1186/s12967-014-0263-5
PMCID: PMC4201925

Genes

MPG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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