Article
The endothelial nitric oxide synthase gene and risk of diabetic nephropathy and development of cardiovascular disease in type 1 diabetes.
Molecular genetics and metabolism - 1 May 2009
Möllsten Anna, Lajer Maria, Jorsal Anders, Tarnow Lise
Abstract excerpt
Nitric oxide (NO) is important in the maintenance of vascular tone and regulation of blood pressure. NO may also play a role in the development of both nephropathy and cardiovascular disease (CVD) in patients with diabetes. The susceptibility to nephropathy and CVD depends to some extent on genetic factors, therefore polymorphisms in the gene coding for endothelial NO-synthase, NOS3, can affect the risk of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
