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Article

A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort.

Human molecular genetics - 15 Jun 2014

Nag Abhishek, Venturini Cristina, Small Kerrin S, Young Terri L, Viswanathan Ananth C, Mackey David A, Hysi Pirro G, Hammond Christopher

Abstract excerpt

Glaucoma is a major cause of blindness in the world. To date, common genetic variants associated with glaucoma only explain a small proportion of its heritability. We performed a genome-wide association study of intra-ocular pressure (IOP), an underlying endophenotype for glaucoma. The discovery...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24518671
DOI: 10.1093/hmg/ddu050
PMCID: PMC4030784

Genes

CAV1
CAV2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24518671-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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