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Article

A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma.

Investigative ophthalmology & visual science - 1 Oct 2017

Ghanbari Mohsen, Iglesias Adriana I, Springelkamp Henriët, van Duijn Cornelia M, Ikram M Arfan, Dehghan Abbas, Erkeland Stefan J, Klaver Caroline C W, Meester-Smoor Magda A

Abstract excerpt

Purpose: To identify microRNAs (miRNAs) involved in primary open-angle glaucoma (POAG), using genetic data. MiRNAs are small noncoding RNAs that posttranscriptionally regulate gene expression. Genetic variants in miRNAs or miRNA-binding sites within gene 3'-untranslated regions (3'UTRs) are expected to affect miRNA function and contribute to disease risk. Methods: Data from the recent genome-wide association...

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Identifiers

PMID: 29049738
DOI: 10.1167/iovs.17-22410
PMCID: PMC6110129

Genes

CARD10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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