Article

Whole-exome sequencing study identifies novel rare variants and genes associated with intraocular pressure and glaucoma

2022-05-29

Abstract excerpt

Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, the leading cause of irreversible blindness worldwide. IOP is also the only modifiable risk factor for glaucoma. Previous genome-wide association studies have established the contribution of common genetic variants to IOP. The role of rare variants for IOP was unknown. Using whole exome sequencing data from 454,756 participants in the UK Biob...

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Literature Corpus work: fe62ebd7-e575-54ed-bee8-78bc953c8840
DOI: 10.1101/2022.05.27.22275601

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