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Article

Single nucleotide polymorphisms within the Wnt pathway predict the risk of bone metastasis in patients with non-small cell lung cancer.

Aging - 26 May 2020

Xu Yiquan, Li Hongru, Weng Lihong, Qiu Yanqin, Zheng Junqiong, He Huaqiang, Zheng Dongmei, Pan Junfan, Wu Fan, Chen Yusheng

Abstract excerpt

The Wingless-type (Wnt) signaling pathway plays an important role in the development and progression of cancer. This study aimed to evaluate the relationship between single nucleotide polymorphisms (SNPs) in the Wnt pathway and the risk of bone metastasis in patients with non-small cell lung cancer (NSCLC). We collected 500 blood samples from patients with NSCLC and genotyped eight SNPs from four core genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Non-Small-Cell Lung

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Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 32453708
DOI: 10.18632/aging.103207
PMCID: PMC7288946

Genes

CTNNB1
APC
AXIN1
WNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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