Article
Wnt pathway activation predicts increased risk of tumor recurrence in patients with stage I nonsmall cell lung cancer.
Annals of surgery - 1 Mar 2013
Shapiro Mark, Akiri Gal, Chin Cynthia, Wisnivesky Juan P, Beasley Mary B, Weiser Todd S, Swanson Scott J, Aaronson Stuart A
Abstract excerpt
OBJECTIVE: To determine the incidence of Wnt pathway activation in patients with stage I NSCLC and its influence on lung cancer recurrence. BACKGROUND: Despite resection, the 5-year recurrence with localized stage I nonsmall cell lung cancer (NSCLC) is 18.4%-24%. Aberrant Wnt signaling activation plays an important role in a wide variety of tumor types. However, there is not much known about the role the Wnt...
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