Article
An oncogenic CTNNB1 mutation is predictive of post-operative recurrence-free survival in an EGFR-mutant lung adenocarcinoma.
PloS one - 1 Jan 2023
Kim Yeseul, Ahn Bokyung, Yoon Shinkyo, Lee Goeun, Kim Deokhoon, Chun Sung-Min, Kim Hyeong-Ryul, Jang Se Jin, Hwang Hee Sang
Abstract excerpt
The Wnt/β-catenin pathway is known to be frequently dysregulated in various human malignancies. Alterations in the genes encoding the components of Wnt/β-catenin pathway have also been described in lung adenocarcinoma. Notably however, the clinical impacts of Wnt/β-catenin pathway alterations in lung adenocarcinoma have not been fully evaluated to date. We here investigated the prognostic implications of single...
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