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Article

Analyses of copy number variation reveal putative susceptibility loci in MTX-induced mouse neural tube defects.

Developmental neurobiology - 1 Sept 2014

Wang Jianhua, Wang Xiuwei, Guan Tao, Xiang Qian, Wang Mingsheng, Zhang Zhi, Guan Zhen, Wang Guoliang, Zhu Zhiqiang, Xie Qiu, Li Guannan, Guo Jin, Wang Fang, Zhang Zhengguo, Niu Bo, Zhang Ting

Abstract excerpt

Copy number variations (CNVs) are thought to act as an important genetic mechanism underlying phenotypic heterogeneity. Impaired folate metabolism can result in neural tube defects (NTDs). However, the precise nature of the relationship between low folate status and NTDs remains unclear. Using an...

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PMID: 24515751
DOI: 10.1002/dneu.22170

Genes

DHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24515751-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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