Article

Integration of epigenomic and transcriptome analyses of neural tube defects reveals methylation driver lncRNAs and mRNAs

2022-04-05

Abstract excerpt

<h4>Background: </h4> Abnormal genome-wide methylation during embryogenesis is associated with neural tube defects (NTDs) at birth. Long noncoding RNAs (lncRNAs) may be promising biomarkers for nervous system-related diseases. Therefore, we aimed to investigate the role of lncRNAs with aberrant methylation in the pathogenesis of NTDs. <h4>Methods: </h4>: Pregnant mice were given retinoic acid (dissolved in corn oi...

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Literature Corpus work: 2b521b0b-b645-5919-ae5f-a906a01d4fb3
DOI: 10.21203/rs.3.rs-1511943/v1

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