Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of p53 and its isoforms in human breast carcinoma cells.

TheScientificWorldJournal - 1 Jan 2014

Milićević Zorka, Bajić Vladan, Živković Lada, Kasapović Jelena, Andjelković Uroš, Spremo-Potparević Biljana

Abstract excerpt

In breast carcinoma, disruption of the p53 pathway is one of the most common genetic alterations. The observation that the p53 can express multiple protein isoforms adds a novel level of complexity to the outcome of p53 mutations. p53 expression was analysed by Western immunoblotting and immunohistochemistry using monoclonal antibodies DO-7, Pab240, and polyclonal antiserum CM-1. The more frequently p53-positive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation

Share to Protein Isoforms

Share to Protein Transport

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 24511294
DOI: 10.1155/2014/618698
PMCID: PMC3913390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of p53 and its isoforms in human breast carcinoma cells.PMID 24511294Read ↗

p53 Isoforms: An Intracellular Microprocessor?Semantic proximity Read ↗

Cytoplasmic p53β Isoforms Are Associated with Worse Disease-Free Survival in Breast Cancer.Semantic proximity Read ↗

Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cellsSemantic proximity Read ↗

Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin.Semantic proximity Read ↗

Association among p53 gene mutation, nuclear accumulation of the p53 protein and aggressive phenotypes in breast cancer.Semantic proximity Read ↗

The relative mRNA expression of p53 isoforms in breast cancer is associated with clinical features and outcomeSemantic proximity Read ↗

Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status.Semantic proximity Read ↗

P53 protein accumulation in non-invasive lesions surrounding p53 mutation positive invasive breast cancers.Semantic proximity Read ↗

An immunochemical analysis of the human nuclear phosphoprotein p53Semantic proximity Read ↗

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.Semantic proximity Read ↗

Distinct tumor protein p53 mutants in breast cancer subgroups.Semantic proximity Read ↗

Comparison of cytosolic p53 protein levels in the female genital tract and breast, and their tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.