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Article

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1992

Moll U M, Riou G, Levine A J

Abstract excerpt

Twenty-seven cases of inflammatory breast cancer were screened for the presence of the p53 protein by immunocytochemical methods using a monoclonal antibody directed against the p53 protein. Three groups were detected: 8 cases (30%) had high levels of p53 in the nucleus of the cancer cells; 9 cas...

Topics

Amino Acid Sequence
Base Sequence
Biomarkers, Tumor
Breast
Breast Neoplasms
Cell Nucleus
Codon
DNA, Neoplasm
Exons
Female
Gene Expression
Genes, p53
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunohistochemistry

Lactation

Molecular Sequence Data

Mutation

Oligodeoxyribonucleotides

Source

Open in PubMed Open full text

Identifiers

PMID: 1353891
DOI: 10.1073/pnas.89.15.7262
PMCID: PMC49686

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1353891-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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