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Article

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1992

Moll U M, Riou G, Levine A J

Abstract excerpt

Twenty-seven cases of inflammatory breast cancer were screened for the presence of the p53 protein by immunocytochemical methods using a monoclonal antibody directed against the p53 protein. Three groups were detected: 8 cases (30%) had high levels of p53 in the nucleus of the cancer cells; 9 cases (33%) had a complete lack of detectable staining; 10 cases (37%) showed a pattern of cytoplasmic staining with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1353891
DOI: 10.1073/pnas.89.15.7262
PMCID: PMC49686

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Source receipt: pubmed, retrieved 7 Sept 2026.

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