Comparison of cytosolic p53 protein levels in the female genital tract and breast, and their tumors.

Abstract excerpt

Under normal conditions, p53 protein is thought to maintain genomic stability. We measured this parameter in healthy tissues from female breast and genital tract using a quantitative, highly sensitive luminometric assay. An organ-specific pattern of p53 expression became evident: breast parenchyma (n = 40, median p53: 0.0346 ng/mg protein) and ovarian tissue (n = 12, 0.063 ng/mg) demonstrated markedly higher p53...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Breast
• Share to Genital Neoplasms, Female