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Article

Combined analysis of exon splicing and genome wide polymorphism data predict schizophrenia risk loci.

Journal of psychiatric research - 1 May 2014

Oldmeadow Christopher, Mossman David, Evans Tiffany-Jane, Holliday Elizabeth G, Tooney Paul A, Cairns Murray J, Wu Jingqin, Carr Vaughan, Attia John R, Scott Rodney J

Abstract excerpt

Schizophrenia has a strong genetic basis, and genome-wide association studies (GWAS) have shown that effect sizes for individual genetic variants which increase disease risk are small, making detection and validation of true disease-associated risk variants extremely challenging. Specifically, we first identify genes with exons showing differential expression between cases and controls, indicating a splicing...

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Source

Identifiers

PMID: 24507884
DOI: 10.1016/j.jpsychires.2014.01.011

Genes

BICD2
DLG3
MCPH1
YWHAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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