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Article

A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients.

Journal of ovarian research - 8 Feb 2014

Zhang Meiying, He Yifeng, Sun Xiangjun, Li Qing, Wang Wenjing, Zhao Aimin, Di Wen

Abstract excerpt

BACKGROUND: Tumor-associated macrophages (TAMs) are classified into two major phenotypes, M1 and M2. M1 TAMs suppress cancer progression, while M2 TAMs promote it. However, little is known regarding the role of TAMs in the development of ovarian cancer. Here, we investigated the relationship between TAM distribution patterns (density, microlocalization, and differentiation) and ovarian cancer histotypes, and we...

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Identifiers

PMID: 24507759
DOI: 10.1186/1757-2215-7-19
PMCID: PMC3939626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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