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Article

Tumor-associated macrophages mediate immune suppression by secreting PD-L1+ exosomes in epithelial ovarian cancer

2019-06-20

Abstract excerpt

<title>Abstract</title> <p>Purpose: To study the role of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) signaling pathway in patients with epithelial ovarian cancer (EOC). <h4>Methods:</h4> A total of 10 EOC specimens and 10 benign ovarian tumor were obtained from surgery and the pathological type. We used the methods of immunofluorescence confocal microscopy, western blot, MTT assay, apoptosis detecti...

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Literature Corpus work
e3f528a0-bc20-5cb8-983d-c5a7de903664
DOI
10.21203/rs.2.10557/v1
Open publication

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Tumor-associated macrophages mediate immune suppression by secreting PD-L1+ exosomes in epithelial ovarian cancerDOI 10.21203/rs.2.10557/v1
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