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Article

Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: a replication study in India.

PloS one - 1 Jan 2014

Anantharaman Devasena, Chabrier Amélie, Gaborieau Valérie, Franceschi Silvia, Herrero Rolando, Rajkumar Thangarajan, Samant Tanuja, Mahimkar Manoj B, Brennan Paul, McKay James D

Abstract excerpt

BACKGROUND: Genetic variants in nicotinic acetylcholine receptor and alcohol metabolism genes have been associated with propensity to smoke tobacco and drink alcohol, respectively, and also implicated in genetic susceptibility to head and neck cancer. In addition to smoking and alcohol, tobacco chewing is an important oral cancer risk factor in India. It is not known if these genetic variants influence propensity...

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Source

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Identifiers

PMID: 24505444
DOI: 10.1371/journal.pone.0088240
PMCID: PMC3914962

Genes

ADH7
ALDH2
CHRNA3
CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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