Article
Polymorphism in ADH and MTHFR genes in oral squamous cell carcinoma of Indians.
Oral diseases - 1 Oct 2008
Solomon P R, Selvam G S, Shanmugam G
Abstract excerpt
OBJECTIVES: Alcohol consumption is known to increase the risk for several cellular disorders like oral cancer. The risk may be reinforced by polymorphism in genes like alcohol dehydrogenase. Therefore, this study is designed to asses the polymorphic status in ADH1B (formerly ADH2), ADH1C (formerly ADH3) and MTHFR genes in order to correlate the susceptibility to oral squamous cell carcinoma (OSCC). SUBJECTS AND...
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