Article
A method for functional trans-complementation of intracellular Francisella tularensis.
PloS one - 1 Jan 2014
Steele Shaun, Taft-Benz Sharon, Kawula Thomas
Abstract excerpt
Francisella tularensis is a highly infectious bacterial pathogen that invades and replicates within numerous host cell types. After uptake, F. tularensis bacteria escape the phagosome, replicate within the cytosol, and suppress cytokine responses. However, the mechanisms employed by F. tularensis to thrive within host cells are mostly unknown. Potential F. tularensis mutants involved in host-pathogen interactions...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
