Article
Spectrum of cognitive impairment in Korean ALS patients without known genetic mutations.
PloS one - 1 Jan 2014
Oh Seong-il, Park Aram, Kim Hee-Jin, Oh Ki-Wook, Choi Hojin, Kwon Min-Jung, Ki Chang-Seok, Kim Hee-Tae, Kim Seung Hyun
Abstract excerpt
BACKGROUND: Cognitive impairment is associated with a negative prognosis in amyotrophic lateral sclerosis (ALS), as well as with clinical specificity. We investigate neuropsychological function in ALS patients without known genetic mutations in a Korean tertiary clinic. METHODS: Three hundred and eighteen patients were enrolled in a prospective longitudinal cohort from September 2008 to February 2012. At the time...
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