Article
Differential Neuropsychological Profile of Patients With Amyotrophic Lateral Sclerosis With and Without C9orf72 Mutation.
Neurology - 5 Jan 2021
Iazzolino Barbara, Peotta Laura, Zucchetti Jean Pierre, Canosa Antonio, Manera Umberto, Vasta Rosario, Grassano Maurizio, Palumbo Francesca, Brunetti Maura, Barberis Marco, Sbaiz Luca, Moglia Cristina, Calvo Andrea, Chiò Adriano
Abstract excerpt
OBJECTIVE: To determine whether the neuropsychological profiles of patients with amyotrophic lateral sclerosis (ALS) with (ALSC9+) and without (ALSC9-) C9orf72 expansion are different, we administered a battery of neuropsychological tests to 741 patients with ALS (68 ALSC9+ and 673 ALSC9-) and 129 controls. METHODS: The study population includes 741 patients with ALS who were consecutively diagnosed at the Turin...
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