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Article

Cognition and motor phenotypes in ALS: a retrospective study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Sept 2022

Aiello Edoardo Nicolò, Pain Debora, Radici Alice, Aktipi Kalliopi Marinou, Sideri Riccardo, Appollonio Ildebrando, Mora Gabriele

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is phenotypically heterogeneous in motor manifestations, and the extent of upper vs. lower motor neuron involvement is a widespread descriptor. This study aimed to examine cognition across different ALS motor phenotypes. METHODS: ALS patients (N = 124) were classified as classical (N = 66), bulbar (N = 13), predominant-upper motor neuron (PUMN; N = 19), and...

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Identifiers

PMID: 35608739
DOI: 10.1007/s10072-022-06157-x
PMCID: PMC9385798

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