Article
N-acetylglucosamine kinase, HXK1 contributes to white-opaque morphological transition in Candida albicans.
Biochemical and biophysical research communications - 28 Feb 2014
Rao Kongara Hanumantha, Ruhela Deepa, Ghosh Swagata, Abdin M Z, Datta Asis
Abstract excerpt
Morphological transition (yeast-hyphal and white-opaque) is an important biological process in the life cycle of pathogenic yeast, Candida albicans and is a major determinant of virulence. Earlier reports show that the amino sugar, N-acetylglucosamine (GlcNAc) induces white to opaque switching in this pathogen. We report here a new contributor to this switching phenomenon, namely N-acetylglucosamine kinase or...
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