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Article

Role of the N-acetylglucosamine kinase (Hxk1) in the regulation of white-gray-opaque tristable phenotypic transitions in C. albicans.

Fungal genetics and biology : FG & B - 1 Jul 2016

Cao Chengjun, Guan Guobo, Du Han, Tao Li, Huang Guanghua

Abstract excerpt

The amino sugar N-acetylglucosamine (GlcNAc) is a host-related environmental cue and a potent inducer of morphological transitions in the human fungal pathogen Candida albicans. It has been well established that GlcNAc promotes white-to-opaque switching and yeast-to-hyphal growth transition primarily through the Ras-cAMP signaling pathway. As a commensal yeast of humans, C. albicans can efficiently use GlcNAc as...

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PMID: 27153757
DOI: 10.1016/j.fgb.2016.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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