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Article

Association of CDKN2A polymorphisms with the severity of cervical neoplasia in a Brazilian population.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2014

Vargas-Torres Sandra Liliana, Portari Elyzabeth Avvad, Klumb Evandro Mendes, Guillobel Heloisa Carneiro da Rocha, de Camargo Maria José, Russomano Fábio Bastos, Macedo Jacyara Maria Brito

Abstract excerpt

Variants of p16(INK4a) and p14(ARF), encoded by the CDKN2A locus, may respond differently to the presence of human papillomavirus (HPV). We investigated the potential association of two CDKN2A polymorphisms, 500C > G (rs11515) and 540C > T (rs3088440), with cervical neoplasia in patients with cervical lesions and healthy controls (n = 492). Polymerase chain reaction-restriction fragment length polymorphism...

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Identifiers

PMID: 24491138
DOI: 10.3109/1354750X.2014.881419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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