Article
Association analysis of p16 (CDKN2A) and RB1 polymorphisms with susceptibility to cervical cancer in Indian population.
Molecular biology reports - 1 Jan 2012
Thakur Nisha, Hussain Showket, Nasare Vilas, Das Bhudev C, Basir Seemi Farhat, Bharadwaj Mausumi
Abstract excerpt
The potent tumor suppressors P16 and RB1 are the key regulators of cell cycle machinery in eukaryotes. Polymorphisms in these genes play an important role in the outcome of various diseases including cancer. In the present study, we evaluated the association of p16 and RB1 polymorphisms with cervical cancer susceptibility in Indian population. We screened 150 histologically confirmed cervical cancer cases along...
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