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Article

Human papillomavirus genotyping and p16INK4a expression in cervical intraepithelial neoplasia of adolescents.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2005

Hu Lulin, Guo Ming, He Zhi, Thornton Justin, McDaniel Larry S, Hughson Michael D

Abstract excerpt

Adolescents have high rates of human papillomavirus (HPV) infection, and persistent high-risk HPV infection can lead to the development of cervical cancer. The cyclin-dependent kinase inhibitor, p16(INK4a) is overexpressed in cervical intraepithelial neoplasia (CIN), probably due to a persistent and integrated HPV infection. This study investigated p16(INK4a) expression, grades of CIN, and high-risk HPV infection...

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Share to Cyclin-Dependent Kinase Inhibitor p16
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Papillomaviridae

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Share to Polymerase Chain Reaction

Share to Uterine Cervical Dysplasia

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 15492761
DOI: 10.1038/modpathol.3800290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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