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Article

Roles of CDKN1A gene polymorphisms (rs1801270 and rs1059234) in the development of cervical neoplasia.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2016

Vargas-Torres Sandra Liliana, Portari Elyzabeth Avvad, Silva Amanda Lima, Klumb Evandro Mendes, da Rocha Guillobel Heloísa Carneiro, de Camargo Maria José, Santos-Rebouças Cíntia Barros, Russomano Fábio Bastos, Macedo Jacyara Maria Brito

Abstract excerpt

The CDKN1A gene product is a p53 downstream effector, which participates in cell differentiation, development process, repair, apoptosis, senescence, migration, and tumorigenesis. The objective of our study was investigated the importance of two polymorphisms in the CDKN1A gene, rs1801270 (31C>A) and rs1059234 (70C>T), for the development of cervical lesions in a Southeastern Brazilian population (283 cases,...

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PMID: 26846214
DOI: 10.1007/s13277-016-4850-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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