Article
CCND1 G870A polymorphism and cervical cancer risk: a case-control study and meta-analysis.
Journal of cancer research and clinical oncology - 1 Mar 2011
Ni Jing, Wang Meilin, Wang Miaomiao, Fu Shilong, Zhou Delan, Zhang Zhengdong, Han Suping
Abstract excerpt
PURPOSE: Cyclin D1 (CCND1) is a key regulatory protein in the G1/S checkpoint of the cell cycle. We hypothesized that the G870A polymorphism of CCND1 is associated with the risk for cervical cancer and performed a meta-analysis of eligible studies to evaluate this relationship. METHODS: In a case-control study of 300 patients with newly diagnosed cervical cancer and 312 cancer-free controls who were...
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