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Article

Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25.

Journal of cardiology - 1 Oct 2017

Ebana Yusuke, Ozaki Kouichi, Liu Lian, Hachiya Hitoshi, Hirao Kenzo, Isobe Mitsuaki, Kubo Michiaki, Tanaka Toshihiro, Furukawa Tetsushi

Abstract excerpt

BACKGROUND: Chromosome 4q25 has been repeatedly identified as atrial fibrillation (AF)-sensitive locus in multiple genome-wide association studies (GWAS) and is considered to hold some clues to AF pathogenesis. We aimed to investigate the clinical utilities in Japanese and to unveil the function of the 4q25 locus in affecting transcription of adjacent genes. METHODS: We conducted AF GWAS in Japanese population...

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Identifiers

PMID: 28087289
DOI: 10.1016/j.jjcc.2016.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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