Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003

Mavilio Domenico, Benjamin Janet, Daucher Marybeth, Lombardo Gabriella, Kottilil Shyam, Planta Marie A, Marcenaro Emanuela, Bottino Cristina, Moretta Lorenzo, Moretta Alessandro, Fauci Anthony S

Abstract excerpt

Natural killer (NK) cells play a central role in host defense against various pathogens. Functional defects of NK cells in HIV-1 infection as a direct effect of abnormal expression or function of inhibitory NK receptors (iNKRs), activating natural cytotoxicity receptors (NCRs), and NKG2D have not yet been described. This study demonstrates an expansion of the functionally defective CD56-/CD16+ population of NK...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to CD56 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down-Regulation

Share to Interferon-gamma

Share to Killer Cells, Natural

Share to Leukocytes, Mononuclear

Share to Receptors, IgG

Share to Transforming Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 14645713
DOI: 10.1073/pnas.2336091100
PMCID: PMC299884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates.PMID 14645713Read ↗

Changes in NK Cell Subsets and Receptor Expressions in HIV-1 Infected Chronic Patients and HIV Controllers.Semantic proximity Read ↗

Natural Killer cells from long-term non-progressor HIV patients are characterized by altered phenotype and function.Semantic proximity Read ↗

The impaired NK cell cytolytic function in viremic HIV‐1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44)Semantic proximity Read ↗

Polyfunctional natural killer cells with a low activation profile in response to Toll-like receptor 3 activation in HIV-1-exposed seronegative subjects.Semantic proximity Read ↗

Treated HIV Infection Alters Phenotype But Not HIV-specific Function of Peripheral Blood Natural Killer CellsSemantic proximity Read ↗

Treated HIV Infection Alters Phenotype but Not HIV-Specific Function of Peripheral Blood Natural Killer Cells.Semantic proximity Read ↗

Specific Phenotypic and Functional Features of Natural Killer Cells From HIV-Infected Long-Term Nonprogressors and HIV ControllersSemantic proximity Read ↗

Phenotypic and functional characteristics of highly differentiated CD57+NKG2C+ NK cells in HIV-1-infected individuals.Semantic proximity Read ↗

Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 control.Semantic proximity Read ↗

NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection.Semantic proximity Read ↗

Elevated Natural Killer Cell Activity Despite Altered Functional and Phenotypic Profile in Ugandans With HIV-1 Clade A or Clade D InfectionSemantic proximity Read ↗

Phenotypically and functionally distinct subsets contribute to the expansion of CD56-/CD16+ natural killer cells in HIV infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.