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Article

Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection.

AIDS research and human retroviruses - 1 May 2011

Mureithi Marianne W, Cohen Kristen, Moodley Ramona, Poole Danielle, Mncube Zenele, Kasmar Anne, Moody D Branch, Goulder Philip J R, Walker Bruce D, Altfeld Marcus, Ndung'u Thumbi

Abstract excerpt

Recent studies suggest that natural killer T (NKT) cells play a role in early antiviral pathogenesis and are rapidly depleted in chronic human immunodeficiency virus type 1 (HIV-1) clade B infection. We aimed to characterize the phenotypic and functional characteristics of NKT cells in HIV-1 clade C-infected Africans at different stages of HIV-1 disease. NKT cell frequencies, subsets, and ex vivo effector...

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Share to Antigens, CD1d
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20942750
DOI: 10.1089/AID.2010.0237
PMCID: PMC3083726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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