Article
Analysis of genomic imprinting by quantitative allele-specific expression by Pyrosequencing(®).
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
McKeown Peter C, Fort Antoine, Spillane Charles
Abstract excerpt
Genomic imprinting is a parent-of-origin phenomenon whereby gene expression is restricted to the allele inherited from either the maternal or paternal parent. It has been described from flowering plants and eutherian mammals and may have evolved due to parental conflicts over resource allocation. In mammals, imprinted genes are responsible for ensuring correct rates of embryo development and for preventing...
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