Article
Pyrosequencing for accurate imprinted allele expression analysis.
Journal of cellular biochemistry - 1 Jul 2015
Yang Bing, Damaschke Nathan, Yao Tianyu, McCormick Johnathon, Wagner Jennifer, Jarrard David
Abstract excerpt
Genomic imprinting is an epigenetic mechanism that restricts gene expression to one inherited allele. Improper maintenance of imprinting has been implicated in a number of human diseases and developmental syndromes. Assays are needed that can quantify the contribution of each paternal allele to a...
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