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Article

Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 28 Jan 2014

Luhur Arthur, Chawla Geetanjali, Wu Yen-Chi, Li Jing, Sokol Nicholas S

Abstract excerpt

Cleavage of microRNAs and mRNAs by Drosha and its cofactor Pasha/DGCR8 is required for animal development, but whether these proteins also have independent roles in development has been unclear. Known phenotypes associated with loss of either one of these two proteins are very similar and consistent with their joint function, even though both cofactors are involved with additional distinct RNA biogenesis...

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Identifiers

PMID: 24474768
DOI: 10.1073/pnas.1318445111
PMCID: PMC3910640

Genes

DGCR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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