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Article

A Genome-Wide RNAi Screen for Factors Involved in Neuronal Specification in Caenorhabditis elegans.

PLoS genetics - 1 Jun 2011

Poole Richard J, Bashllari Enkelejda, Cochella Luisa, Flowers Eileen B, Hobert Oliver

Abstract excerpt

One of the central goals of developmental neurobiology is to describe and understand the multi-tiered molecular events that control the progression of a fertilized egg to a terminally differentiated neuron. In the nematode Caenorhabditis elegans, the progression from egg to terminally differentiated neuron has been visually traced by lineage analysis. For example, the two gustatory neurons ASEL and ASER, a...

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PMID: 21698137
DOI: 10.1371/journal.pgen.1002109
PMCID: PMC3116913

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