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Article

Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment.

Drug and alcohol dependence - 1 Mar 2014

Schottenfeld Richard S, Chawarski Marek C, Cubells Joseph F, George Tony P, Lappalainen Jaakko, Kosten Thomas R

Abstract excerpt

BACKGROUND: Disulfiram may be efficacious for treating cocaine dependence or abuse, possibly through inhibiting dopamine β-hydroxylase (DβH). Consequently, this randomized, placebo-controlled clinical trial of disulfiram during buprenorphine maintenance treatment evaluated the study hypothesis that disulfiram is superior to placebo and explored whether disulfiram response is greatest for participants with a...

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Identifiers

PMID: 24462581
DOI: 10.1016/j.drugalcdep.2013.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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