A delta-opioid receptor genetic variant is associated with abstinence prior to and during cocaine dependence treatment.

doi:10.1016/j.drugalcdep.2016.07.008

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Article

A delta-opioid receptor genetic variant is associated with abstinence prior to and during cocaine dependence treatment.

Drug and alcohol dependence - 1 Sept 2016

Crist R C, Doyle G A, Kampman K M, Berrettini W H

Abstract excerpt

INTRODUCTION: An intronic polymorphism in the delta-opioid receptor gene (OPRD1) was previously associated with cocaine dependence in African-Americans. However, it is not known if the polymorphism (rs678849) is associated with dependence-related phenotypes within the cocaine dependent population. METHODS: Cocaine and alcohol dependent subjects were randomized to either topiramate or placebo. Abstinence from...

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Identifiers

PMID: 27449273
DOI: 10.1016/j.drugalcdep.2016.07.008
PMCID: PMC4983478

Genes

OPRD1

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