Article
Pharmacogenetics of naltrexone and disulfiram in alcohol dependent, dually diagnosed veterans.
The American journal on addictions - 1 Jan 2000
Arias Albert J, Gelernter Joel, Gueorguieva Ralitza, Ralevski Elizabeth, Petrakis Ismene L
Abstract excerpt
BACKGROUND: Disulfiram and naltrexone were evaluated in treatment of individuals with co-occurring alcohol dependence and other Axis I disorders (e.g., Major Depression). We explored pharmacogenetic interactions in genotyped subjects. METHODS: Alcohol dependent (AD) subjects received naltrexone alone, placebo alone, disulfiram with placebo or disulfiram with naltrexone. They were genotyped for OPRM1 rs1799971...
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