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Article

ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse.

Pharmacogenetics and genomics - 1 Jul 2013

Spellicy Catherine J, Kosten Thomas R, Hamon Sara C, Harding Mark J, Nielsen David A

Abstract excerpt

OBJECTIVE: Disulfiram is a potential cocaine addiction pharmacotherapy. Since dopamine deficiency has been found with cocaine addiction, our objective was to examine whether functional variants in the ankyrin repeat and kinase domain-containing 1 (ANKK1) and/or the dopamine receptor D2 (DRD2) genes interact with response to treatment with disulfiram. MATERIALS AND METHODS: Cocaine and opioid codependent (DSM-IV)...

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Share to Receptors, Dopamine D2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23635803
DOI: 10.1097/FPC.0b013e328361c39d
PMCID: PMC5396392

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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