Article
Enhancement of endothelial cell migration by constitutively active LPA(1)-expressing tumor cells.
Biochemical and biophysical research communications - 1 Jun 2012
Kitayoshi Misaho, Kato Kohei, Tanabe Eriko, Yoshikawa Kyohei, Fukui Rie, Fukushima Nobuyuki, Tsujiuchi Toshifumi
Abstract excerpt
Lysophosphatidic acid (LPA) receptors belong to G protein-coupled transmembrane receptors (LPA receptors; LPA(1) to LPA(6)). They indicate a variety of cellular response by the interaction with LPA, including cell proliferation, migration and differentiation. Recently, we have reported that constitutive active mutated LPA(1) induced the strong biological effects of rat neuroblastoma B103 cells. In the present...
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